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A single-nucleus multiomic and spatial atlas of gene regulation in human spermatogenesis
A single-nucleus multiomic and spatial atlas of human spermatogenesis is generated by profiling chromatin accessibility and gene expression in the same nuclei and integrating these data with spatial transcriptomics of intact testicular tissue, providing a spatially resolved regulatory framework for human spermatogenesi...
HIPK4 is a novel gene associated with teratozoospermia and male infertility
HIPK4 is an autosomal-recessive candidate gene associated with sperm head defects and male infertility and is an autosomal-recessive candidate gene associated with sperm head defects and male infertility.