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Author

Fa-Guang Zhang

2 papers indexed here

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Sep 2026

Cu‐Catalyzed Controllable Single and Double Hydrophosphination of Trifluoromethyl 1,3‐Enynes †

Fluorinated organophosphorus compounds are highly valuable in transition‐metal catalysis and medicinal chemistry. Despite their significance, synthetic methods through catalytic hydrophosphination of β‐CF 3 ‐1,3‐enynes remain unexplored, particularly for divergent synthesis of structurally distinct phosphine deri...

Yong-Xin Teng, Xiao-Li Huang, Xiao-Dong Tang et al. · 0 citations
Jul 2026

Biosynthesis of Fluorinated Aromatic Polyketides Through Directed Evolution of Fused Type III Polyketide Synthase.

A series of combinational optimization strategies, including metabolic regulations, double protein fusion, and directed evolution of the rate-limiting enzymes, were conducted to improve the production of fluoro-aromatic polyketides, thus enhancing the titers to >200 mg/L from an initial ∼10 mg/L.

Ze-Long Mei, Jia-Xin Guo, Zhou-Tong Sun et al. · 0 citations

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