Mitochondrial pearling: membrane biophysics, Ca2+-dependent regulation, mtDNA nucleoid dynamics, and emerging links to mitochondrial quality control and neurological disorders
Evidence does not yet establish a continuous sequence from pearling through coordinated outer- and inner-membrane scission to mitophagy or intercellular mitochondrial transfer, so the provisional term “candidate disease-associated sustained pearling phenotype” is used only for within-study events that meet dynamic pear...