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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Fabian Gossen

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Open access Sep 2026

Mechanism of GPR84 allosteric modulation at a helix 8–proximate site

Allosteric modulators offer opportunities for pathway-selective G protein–coupled receptor (GPCR) signaling, but the mechanisms enabling biased allosteric modulation remain poorly understood. We identify a helix 8–proximate allosteric site in the immune-metabolic receptor GPR84 and define how it achieves Gi-biased sign...

Xuan Zhang, Abdul-Akim Guseinov, Laura Jenkins et al. · 0 citations

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