Control of Intestinal Type 3 Immunity by the Unfolded Protein Response Sensor IRE1 in Antigen Presenting Cells.
BACKGROUND AND AIMS The unfolded protein response (UPR) is an essential cellular program maintaining intestinal homeostasis by acting on several cell types. However, whether the UPR sensor IRE1 acts on dendritic cells (DCs) and other antigen presenting cells (APCs) for shaping intestinal immunity remains poorly defined...