Hydroxyurea (HU) is an established anticancer drug used to treat chronic myelogenous leukemia, but its therapeutic efficacy is limited by rapid clearance, variable bioavailability, and dose-related toxicity. This study aimed to improve HU delivery by developing hydroxyurea-loaded nanostructured lipid carriers (NLCs) us...
O. Madkhali, Mohammad Intakhab Alam, Syam Mohan et al.· Journal of Visualized Experi...· 0 citations
CA4 is prioritized as a reproducible LUAD-associated candidate supported by transcriptomic, machine-learning, immune, survival, and docking evidence, but the computational findings do not demonstrate direct phytochemical regulation of CA4 or therapeutic efficacy.
Awaji Y. Safhi, Fahad Y. Sabei, Ali Hanbashi et al.· Journal of Pharmaceutical In...· 0 citations
Polysaccharide-based drug delivery systems have to be closely watched in terms of drug release in the body over time if they want to be able to achieve maximum therapeutic effectiveness and maintain controlled bioavailability. The work presents a data-driven framework that employs Raman spectroscopy and uncertainty...
Ahmed H. Albariqi, Awaji Y. Safhi, Fahad Y. Sabei et al.· Scientific Reports· 0 citations
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