Open access
Sep 2026
Kidney fibrosis is mediated by GARP-restricted TGF-β activation in fibroblasts.
GARP-mediated release of active TGF-β is identified as a critical step in sustaining fibroblast activation during kidney fibrosis and highlight GARP as a promising therapeutic target for CKD.
Yin-Tong Chen, Wei-Wei Xu, Jie-Li Yu et al.
· JCI Insight · 0 citations