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Open access Sep 2026

Amphotericin B-loaded polyphenolic nanoparticles for synchronous fungal eradication and immunomodulation in treating superficial fungal infections

Fungal infection represents an escalating global health threat, yet effective treatment remains clinically challenging due to the poor solubility, limited bioavailability, and pronounced cytotoxicity of conventional antifungal agents. To overcome these limitations, a self-assembled nanoparticle (ATE NPs) is developed b...

Yong-Nan Chen, Fu-Yao Chen, Shi-Ya Wang et al. · 0 citations
Sep 2026

Synchronous Metabolic Interference and Immune Reprogramming by a Self-Assembled Bismuth–Phenolic Nanoparticle against Pseudomonas aeruginosa -Induced Infections

Effective eradication of Pseudomonas aeruginosa (P. aeruginosa) infection remains challenging due to its multifaceted antibiotic resistance mechanisms and biofilm-associated protection. Furthermore, inflammatory dysregulation within the infected microenvironment compromises both antibacterial efficacy and tissue repa...

Hao-Jie Chen, Rou-Ye Wang, Fang Liu et al. · 0 citations
Open access Jul 2026

Anion‐π Interaction‐Triggered Self‐Healing Zwitterionic Hydrogel as an Immunocompatible Platform for Injectable Therapies

An injectable zwitterionic supramacromolecular hydrogel (SSH) is reported, formed by the spontaneous assembly of poly(methacryloyloyloxyethyl sulfobetaine) and poly(styrenesulfonate) (PSSNa), which exhibits injectability, self‐healing behavior, intrinsic antiadhesive properties, and favorable immunocompatibility.

Zi-Hao Zhu, Zu-Ping Xiong, Ke-Xin Chen et al. · 2 citations

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