Fungal infection represents an escalating global health threat, yet effective treatment remains clinically challenging due to the poor solubility, limited bioavailability, and pronounced cytotoxicity of conventional antifungal agents. To overcome these limitations, a self-assembled nanoparticle (ATE NPs) is developed b...
Yong-Nan Chen, Fu-Yao Chen, Shi-Ya Wang et al.· Materials Today Bio· 0 citations
Effective eradication of Pseudomonas aeruginosa (P. aeruginosa) infection remains challenging due to its multifaceted antibiotic resistance mechanisms and biofilm-associated protection. Furthermore, inflammatory dysregulation within the infected microenvironment compromises both antibacterial efficacy and tissue repa...
Hao-Jie Chen, Rou-Ye Wang, Fang Liu et al.· ACS Nano· 0 citations
An injectable zwitterionic supramacromolecular hydrogel (SSH) is reported, formed by the spontaneous assembly of poly(methacryloyloyloxyethyl sulfobetaine) and poly(styrenesulfonate) (PSSNa), which exhibits injectability, self‐healing behavior, intrinsic antiadhesive properties, and favorable immunocompatibility.