Direct Cytosolic Protein Delivery via Near-Infrared-Driven Membrane-Intercalating Conjugated Oligoelectrolytes
The intracellular delivery of functional proteins remains a major challenge due to the impermeability of the plasma membrane and inefficient endosomal escape. Here, we report a membrane-intercalating conjugated oligoelectrolyte (MI-COE, BBTN) that enables near-infrared (NIR)-triggered direct cytosolic protein deliver...