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Review Open access Sep 2026

Targeting subchondral osteoporosis in osteoarthritis: biomechanical crosstalk and the therapeutic rationale for inflammatory microenvironment remodeling

Current osteoarthritis (OA) management remains largely symptom-directed, while the contribution of osteoporosis (OP)-related and OA-associated subchondral remodeling to disease heterogeneity remains uncertain. This review integrates macroscopic load redistribution and lower-limb malalignment with local osteoimmune proc...

Ming-Li Han, Long-Fei Han, Su-Yan Zhang et al. · 0 citations
Open access Aug 2026

Preoperative CT-derived thigh muscle quality as a predictor of postoperative outcomes after total knee arthroplasty in patients with hemophilia

Preoperative CT-derived thigh muscle quality was independently associated with 1-year functional recovery after TKA in haemophilic arthropathy and may support preoperative risk stratification.

Rui Feng, Jia-qi Yang, Yang Liu et al. · 0 citations

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