Author

Fang-Ni Chai

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

PPM1L-dependent PD-L1 dephosphorylation orchestrates tumor-type-specific ubiquitin ligase recognition to govern its degradation.

As a powerful clinical strategy for cancer treatment, immune checkpoint blockage targeting the PD-1/PD-L1 axis is frequently hampered by diverse resistance mechanisms. An in-depth elucidation of the molecular mechanisms governing PD-L1 homeostasis is crucial for improving the immunotherapy response rate. Here, we demon...

Pan Li, Xin Liu, Ping Hu et al. · Cell Reports · 0 citations

Open access Sep 2026

Site-specific programming characterizes dynamic post-translational acetylation of histone H2B lysine 108 in mouse embryonic stem cells

Dynamic histone modifications are critical for regulating stem cell fate. However, generalized strategies for site-specific programming of histone modifications profiling on unperturbed chromatin in embryonic stem cells (ESCs) remain challenging. In this study, we established a genetic code expansion-based platform in...

Fang-Ni Chai, Qin Huang, Li Zhou et al. · Nature Communications · 0 citations