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Open access Sep 2026

FABP4 characterizes metabolic–immune interactions and serves as a prognostic biomarker across gynecologic malignancies: a multi-omics integrative analysis

Highlights • FABP4 is broadly downregulated across five gynecologic malignancies.• Promoter hypermethylation is associated with reduced FABP4 expression.• High FABP4 marks poor ovarian/cervical but favorable endometrial outcomes.• Single-cell and spatial data link stromal FABP4 to metabolic–immune crosstalk.• FABP4 kno...

Fang-Fang Chen, Li-Feng Dong, Sai-Sa Zhu et al. · 0 citations
Aug 2026

Graph attention-guided multi-modal learning for high-throughput screening of environmental chemicals associated with breast cancer risk.

The rapid expansion of chemical production and use has increased human exposure to environmental chemicals that can impact biological pathways relevant to mammary carcinogenesis. This trend creates an urgent need for scalable screening tools that can identify chemicals of potential concern before extensive animal testi...

Yu Qiu, Yi-Qu Wu, Fang Wan et al. · 0 citations

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