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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Fang Zhao

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3 papers indexed here

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Open access Oct 2026

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Findings reveal that MD‐1 promotes pro‐inflammatory (M1‐like) macrophage polarisation in atherosclerosis by inhibiting NLRP3 inflammasome activation via a cGAS‐STING dependent pathway and suggest that MD‐1 neutralisation could be a potential therapeutic strategy for atherosclerosis management.

Fang Zhao, Zhi-Li Jin, Zhi-Wei Cai et al. · 0 citations
Open access Sep 2026

idTAG enables programmable and physiologically faithful control of endogenous protein degradation

Rapid and precise depletion of endogenous proteins is essential for dissecting gene function, yet existing degron technologies often require direct modification of endogenous coding sequences, which can compromise protein expression and limit their applicability. Here, we develop idTAG, an inducible degron platform tha...

Mingkui San, Jia-Kun Peng, Fang Zhao et al. · 0 citations
Aug 2026

Lanthanide Metal-Organic Frameworks Enable Target-Triggered CRISPR-Cas12a Activator Release for Ultrasensitive Non-nucleic Acid Biomarker Detection.

A modular fluorescence signal transduction platform integrating aptamer-functionalized magnetic beads, lanthanide metal-organic frameworks, and CRISPR-Cas12a-mediated collateral cleavage amplification for sensitive cTnI detection, providing a universal strategy to expand CRISPR-Cas systems toward non-nucleic acid targe...

Yongzhen Liu, Long Yu, Yongjin Shen et al. · 0 citations

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