Open access
Aug 2026
Gadd45a knockout alleviates cisplatin-induced hearing loss by inhibiting CXCL family protein expression
Background Cisplatin is a widely used chemotherapeutic agent, but its clinical application is limited by serious ototoxic side effects, including hearing loss, tinnitus, and vertigo. Inflammation is now recognized as a significant contributor to cisplatin-induced hearing loss, but the upstream regulators remain largely...
Weilong Wang, Shengyu Zou, Danqi Wang et al.
· Military Medical Research · 0 citations