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Author

Fangming Zhang

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Open access Oct 2026

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

ABSTRACT Detection of gene mutations related to acute myeloid leukemia (AML) is crucial for its early diagnosis, personalized treatment, and recurrence monitoring. However, accurate detection of diverse mutations occurring at the same locus remains technically challenging. The CRISPR/Cas system, with its unique program...

Lin-Lin Bai, Bei Wang, Ming-Ming Shi et al. · 0 citations
Aug 2026

Rapid Broad-Spectrum Colorimetric Detection of Bacteria Using Polylysine-Mediated Gold Nanoparticle Aggregation.

Rapid on-site detection of bacterial contamination remains an urgent need in public health and environmental monitoring. Herein, we report a one-step, label-free colorimetric sensor for broad-spectrum bacterial detection based on a competitive electrostatic mechanism. Cationic poly-l-lysine (PLL) induces the aggregatio...

Bo-Zhou Chen, Yu Wu, Fangming Zhang et al. · 0 citations

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