Author

Fanny M. Elahi

2 papers indexed here

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Open access Sep 2026

Plasma Biomarker Effects of Oral Valiltramiprosate/ALZ-801 in Early Alzheimer’s Disease from Phase 3 and Phase 2 Trials: Analysis of Core Biomarkers and Correlations with Clinical and Neuroimaging Outcomes

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with few treatment options, especially for APOE4/4 homozygotes who carry high genetic risk. Valiltramiprosate/ALZ-801 is an oral small-molecule inhibitor of amyloid-beta oligomer formation in late-stage development as a disease-modifying therapy for A...

J. Hey, S. Abushakra, A. Power et al. · Drugs · 0 citations

Open access Aug 2026

CSF fibrinogen predicts longitudinal Tau accumulation in cognitively unimpaired older adults

Blood–brain barrier (BBB) dysfunction is an early feature of Alzheimer's disease (AD). Fibrinogen represents a sensitive marker of BBB leakage, but whether it modifies longitudinal tau progression in cognitively unimpaired (CU) individuals remains unknown.

C. Lisgaras, Tovia Jacobs, L. Figueredo et al. · Alzheimer's & Dementia · 0 citations