Predictive Amphiphile Design Enables Control of Self-Assembled Nanoparticle-Cell Membrane Interactions.
Despite decades of development, the clinical translation of amphiphilic self-assembled nanoparticles remains limited by the lack of a predictive molecular design framework, owing to the complex, dynamic behavior of nanoparticles and cell membranes. Here, we introduce a building-block design strategy focused on amphiphi...