Open access
Sep 2026
STING-mediated tumor microenvironment remodeling: turning adaptive resistance into therapeutic vulnerability
Resistance to cancer immunotherapy is frequently sustained by immune exclusion, suppressive myeloid and stromal programs, abnormal tumor vasculature, and inhibitory checkpoint-ligand expression within the tumor microenvironment. Activation of the cGAS-STING (cyclic GMP-AMP Synthase)- (Stimulator of Interferon Genes) pa...
Akash R. Boda, E. Bolli, A. Salameh et al.
· Frontiers in Immunology · 0 citations