Author

Federica Ricciardi

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Open access Oct 2026

Adolescent social isolation drives sex-dependent shifts in medial prefrontal cortex endocannabinoid tone and excitatory/inhibitory balance: the protective role of a methyl donor.

Prolonged social isolation triggers neuropsychiatric impairments linked to brain neurotransmitter imbalances. This study investigated the impact of social isolation on sensory perception, affective states, and the levels of amino acid neurotransmitters and endocannabinoids within the medial prefrontal cortex (mPFC) of...

Federica Ricciardi, Laura Mosca, C. Belardo et al. · Neuropharmacology · 0 citations

Open access Oct 2026

The Nucleus Accumbens Dorsomedial Column: Distinct Anterior–Posterior Inputs and Activation Inversely Associated With Opioid Relapse

Anatomical studies suggest that a dorsomedial region of the nucleus accumbens (dmACB) forms a basal ganglia‐like closed‐loop circuit with medial ventral pallidum (mVP), lateral hypothalamic area (LHA), and paraventricular thalamic nucleus (PVT). The circuit's topographic organization is unknown. We first used anterogra...

Kenichiro Negishi, Vanessa I. Navarro, Mona S. Pishgar et al. · The Journal of comparative n... · 0 citations

Review Open access Oct 2026

ER-Nε-lysine acetylation machinery in neurological disorders: A context-dependent regulator of proteostasis.

Despite extensive characterization of cytosolic and nuclear acetylation, the functional relevance of luminal ER-Nε-lysine acetylation in the nervous system remains poorly understood. This modification is mediated by a coordinated metabolic-secretory axis involving acetyl-CoA availability and the ER-resident acetyltrans...

Emanuele Di Martino, R. A. de Vos, Sofia Koenig Gimeno et al. · Current Opinion in Chemical... · 0 citations