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Fei-Fei Zhou

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Open access Jul 2026

Hidden genetic diversity in 320 nearly-complete East Asian genome assemblies

East Asian populations, representing over 20% of the global population, remain critically underrepresented in human genomic studies, limiting our understanding of population-stratified genetic variation and its implications for health and disease. Here we present the first phase of the Asian Pan-Genome project (APG), c...

Dongya Wu, Chentao Yang, Quanyu Chen et al. · bioRxiv · 2 citations

Open access Aug 2026

Cross-species discovery of large structural variants reveals distinct evolutionary dynamics in primates

LGvar is presented, a divergence-aware tool for identifying SVs in population-scale and cross-species genome assemblies, enabling up to a 7-fold increase in the detection of large deletions, insertions, inversions and complex rearrangements.

Fei-Fei Zhou, Junmin Han, Shilong Zhang et al. · bioRxiv · 0 citations