Author

Fei Lin

2 papers indexed here

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Open access Aug 2026

TRIM59 Drives Bladder Cancer Progression Through E3 Ligase‐Dependent K48‐Linked Degradation of PTRF

A previously unrecognized TRIM59–PTRF–AKT/c‐Myc axis that drives BLCA progression is defined and TRIM59 is highlighted as a potential prognostic biomarker and therapeutic target.

Junlin Gan, Xuesong Bai, Aijie Zhang et al. · Cancer Science · 0 citations

Jul 2026

Ambient PM2.5 exposure is associated with clear cell renal cell carcinoma aggressiveness and promotes tumor progression through ROS-mediated AKT/HIF-2α signaling.

Ambient fine particulate matter (PM2.5) is an established environmental health hazard, but its role in clear cell renal cell carcinoma (ccRCC) progression remains incompletely understood. This study integrated epidemiological analysis, mechanistic experiments, transcriptomic profiling, and clinical tissue validation to...

Xiao-Hui Wu, Wen-Cai Zheng, Wen-Tao Xu et al. · Chemico-Biological Interacti... · 0 citations