Interactive clinical agents operate under partial observability, so reliable care depends on reaching the correct diagnosis through evidence-grounded, safe interactions. Yet existing agents struggle to convert experience into reusable process knowledge with explicit provenance and authority. To address this gap, we introduce MediSkill-Evo, which self-evolves governed process knowledge without fine-tuning the backbone. It realizes this self-evolution by updating clinical, process, symbolic, and visual knowledge in four typed banks under type-specific validation and scope rules. The Process-Constrained Preference Harness then turns validated knowledge into action by grounding candidates in evidence and prioritizing safer decisions. We evaluate on 300 MIMIC-IV-derived FullChain encounters, 180 hard-isolation conditions covering six process obligations, and 100 multimodal NEJM image-diagnosis cases. On Qwen FullChain, MediSkill-Evo improves diagnosis accuracy by 7.81% and treatment-intent coverage by 70.67% over the best-performing prior agent, while reducing critical failures by 43.04%. Under stress, it improves the stress-process composite by 7.77% and required-action completion by 12.41% over the best-performing agent for each metric, with stronger patient-fact, temporal-evidence, and triage-red-flag recovery and no controller-scored errors in unavailable-evidence, treatment, and triage safety checks. On multimodal NEJM diagnosis, MediSkill-Evo with optional MedSAM localization improves diagnosis accuracy by 2.56% and core score by 18.96% over the best-performing memory agent. Code is available at https://anonymous.4open.science/r/mediskill-evo_anonymous-68E7.
Ruoyu Wu, Shenfu Xie, Yinqian Sun et al.· 0 citations
Safety tuning can improve harmful refusal, but models may learn surface-form shortcuts: wrapped harmful prompts bypass safety, while similarly wrapped benign prompts are over-refused. We propose Wrapper-Based Intent-Form Augmentation (WIFA), an automatic intent-group augmentation method that pairs wrapped harmful examples with structurally matched wrapped benign counterexamples, requiring no external teacher or manual per-wrapper intent labels. We use WIFA as a common data layer for two complementary fine-tuning routes: WIFA-Boost, a two-stage high-safety recipe, and Anchored Group-Consistent Refusal Training (A-GCRT), which regularizes refusal/compliance decision scores across same-intent wrappers and anchors harmful and benign groups on opposite sides of a margin. In the Qwen setting, WIFA-Boost reaches the strongest transformed-harmful refusal, while A-GCRT reduces OR-Bench over-refusal from 25.7\% for the base model to 17.4\%; reproduced baselines do not match these operating points. Llama results and ablations over data structure, two-stage order, and A-GCRT components support this intent-group interpretation without claiming universal below-base over-refusal.
Ping Wu, Haibo Tong, Feifei Zhao et al.· 0 citations
ForesightSafety-TIDE, a controlled evaluation framework that strictly pairs all-honest collaboration with controlled deception by a key evidence holder and analyzes the aggregation process through multi-stage voting, testimony adoption, and evidence-root lineage propagation, reveals both the fragility of distributed fact recovery and its underlying mechanism.
Chen Yan, Zeyang Yue, Feifei Zhao et al.· 0 citations
DiverValue-Bench is introduced, a population-aware benchmark for evaluating multi-dimensional value alignment across 74 countries/regions and it is shown that lightweight preference-based fine-tuning with Low-Rank Adaptation and Direct Preference Optimization substantially improves in-domain value alignment while yielding consistent out-of-domain gains.
Yao Liang, Dongcheng Zhao, Feifei Zhao et al.· 0 citations