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Author

Felix Bender

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Sep 2026

Inositol hexakisphosphate is a Cofactor and Modulator of ADAR1 RNA Editing Activity.

Adenosine-to-inosine (A-to-I) RNA editing by ADAR1 is a key post-transcriptional modification, and mutations in ADAR1 lead to Aicardi-Goutières syndrome (AGS), an autoimmune disorder. Despite its biological and clinical relevance, the regulation of ADAR1 activity remains incompletely understood. Using a combination of...

Francisco Antonio Venegas Solis, Mengsi Lu, Roni Cohen-Fultheim et al. · 0 citations

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