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Author

Felix Mueller

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Open access Jul 2026

DICER1-related tumour predisposition mutations increase 3p-miRNA function and HERVH activity

It is shown that cancer-associated DICER1 mutations shift microRNA processing and reactivate HERVH endogenous retroviruses and cause upregulation of transposable elements, including the human endogenous retrovirus H through miRNA-independent mechanisms.

K. Gordon, N. Bellora, Jeroen Witteveldt et al. · 0 citations

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