Tumor necrosis factor receptor-associated factors (TRAFs) are key signaling proteins involved in cellular innate immune pathways. However, knowledge of TRAF genes in echinoderms remains limited. We cloned a novel TRAF gene (SiTRAF) from the sea urchin Strongylocentrotus intermedius. The full-length open reading frame o...
Feng-Cheng Liu, Tong Liu, Xiao-Long Chu et al.· Fish and Shellfish Immunolog...· 0 citations
A novel "dual-track" regulatory model is proposed to resolve the conflicting roles of estrogen in tumor immunity and novel molecular targets are uncovered to improve combined endocrine and immunotherapeutic regimens for breast cancer patients.
Dana R. Crawford, Yung-Ning Yang, Feng-Cheng Liu et al.· Biomedicine & pharmacotherap...· 0 citations
Investigation of the antiviral properties and underlying mechanism of trehalose 6‐monolaurate against Sindbis virus establishes TML as a host‐directed inhibitor acting at post‐entry stages of alphavirus replication and underscores its potential as a lead scaffold for the development of therapeutics against mosquito‐bor...
Jeng-Wei Lu, M. Helal, Guan-Chiun Lee et al.· Journal of Medical Virology· 0 citations
The identification of a novel TLR gene in Chlamys farreri and analysis of its immune functions expand the knowledge of the role of TLR in mollusk immunity and may provide evidence for selecting disease-resistant scallops for cultivation.
Jilv Ma, Feng-Cheng Liu, Zi-Hao Zhang et al.· Developmental and Comparativ...· 0 citations
SiTRAF3 is identified as a pivotal scaffold protein in the echinoid innate immune system, as it significantly drove the promoter activities of nuclear factor kappa-B, activator protein-1, signal transducer and activator of transcription 3, along with multiple inflammatory cytokines and interferon-related elements.
Xiao-Long Chu, Feng-Cheng Liu, Yingying Liu et al.· Fish and Shellfish Immunolog...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
