Protein aggregation is a pathological process associated with several human diseases termed proteinopathies, including neurodegenerative and metabolic disorders such as Alzheimer’s disease, Parkinson’s disease, type II diabetes, amyotrophic lateral sclerosis, and Huntington’s disease. In these conditions, specific pr...
Danilo Milardi, Jiyeon Han, Hyuck Jin Lee et al.· Chemical Reviews· 0 citations
Biofilm-associated functional amyloids reinforce extracellular matrices and enhance microbial resistance to environmental and antimicrobial stresses. In Staphylococcus aureus, phenol-soluble modulins (PSMs), particularly the PSM-α family, regulate biofilm maturation and pathogenicity through sequence-dependent self-ass...
Feng-Juan Huang, Yi-Ran Wang, Hao Sun et al.· Colloids and Surfaces B: Bio...· 0 citations
Amyloid aggregation into polymorphic fibrils is central to many neurodegenerative and systemic diseases, yet the physical origins of fibril polymorphism and time-dependent morphological evolution remain unclear. Because mature fibril morphologies are separated by high energy barriers, direct interconversion is unlikely...
Kamal Bhandari, Wuzhou Xiong, Tianyi Hou et al.· Journal of Physical Chemistr...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
