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Review Open access Aug 2026

Decoding the molecular mechanisms of pyroptosis and its therapeutic development prospects

Pyroptosis is an emerging form of inflammatory programmed cell death primarily mediated by the gasdermin protein family, characterized by cell swelling, membrane pore formation, and the release of pro-inflammatory cytokines such as IL-1β and IL-18. This mode of cell death has garnered significant attention due to its c...

Yi Shen, Qiang-Qiang Zheng, Yang Yuan et al. · 0 citations

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