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Review Open access Nov 2026

Combined Pulmonary Fibrosis and Emphysema: Current Status and Future Perspective

ABSTRACT Background Combined pulmonary fibrosis and emphysema (CPFE) is a clinical syndrome defined by the coexistence of upper‐lobe emphysema and lower‐lobe pulmonary fibrosis. It is characterized by clinical, functional, and radiologic features that differ significantly from isolated idiopathic pulmonary fibrosis or...

Qin-Yu Deng, C.-G. Chen, Q. Zhang et al. · 0 citations
Open access Oct 2026

Mesothelial plasticity regulates lung mechanical homeostasis in regeneration and fibrosis.

The mesothelium is redefine the mesothelium as a mechanosensitive regulator of organ-scale mechanical adaptation and reveal how pleural surface remodeling controls tissue mechanics during regeneration and disease.

Gui-Lin Yang, Jun-Yu Mou, Zhi-Xin Li et al. · 0 citations
Open access Oct 2026

Alveolar stem cells transdifferentiate to drive bronchiolar regeneration

The lung consists of two anatomically distinct compartments: the airways and the alveoli. Although airway epithelial stem cells are known to mobilize for alveolar regeneration, whether alveolar cells can reciprocally traverse these anatomical boundaries and contribute to bronchial repair remains unclear1, 2, 3–4. Here...

Kuo Liu, Zi-Xin Liu, Xin-Feng Meng et al. · 0 citations

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