Twenty-year persistence of SARS-CoV-1 immune imprinting shapes antibody responses to SARS-CoV-2 infection.
Study of individuals sequentially infected with SARS-CoV-1 and SARS-CoV-2 over two decades and found durable imprinting of antibody responses following SARS-2 BF.7 breakthrough infection defines the remarkable longevity and molecular basis of antibody imprinting and provides insights for pan-sarbecovirus vaccine design...