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Sep 2026

Engineered cryo-shocked tumor cells recruit T cells for lung cancer immunotherapy.

Immune checkpoint blockade has transformed cancer therapy, yet its efficacy against solid tumors remains constrained by poor T cell infiltration and an immunosuppressive tumor microenvironment. Achieving localized and sustained chemokine signaling without systemic immune toxicity remains a central unmet challenge for c...

Hui-Heng Feng, Feng Liu, Ze-Sheng Cheng et al. · 0 citations
Aug 2026

Mussel-Inspired Membrane Encapsulation Strategy for Developing Long-Acting Glucose-Responsive Injectable Insulin Crystals.

Inspired by the catechol-lysine synergy and oxidative cross-linking mechanisms in mussel adhesion, we have synthesized poly-l-lysine (PLL) modified with 3,4-dihydroxyphenylacetic acid (DOPAC) to encapsulate insulin crystals. Upon oxidation, a dense, stable, and uniform membrane with nanochannels is in situ formed on th...

Jian-Chang Xu, Yanfang Wang, Jingyi Chen et al. · 0 citations

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