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Feng Liu

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Open access Aug 2026

The dual role of APOE ε4 allele in cerebral small vessel disease: independent genetic effects and effect modification of traditional risk factors

Background The association between apolipoprotein E (APOE) ε4 and cerebral small vessel disease (CSVD) remains incompletely understood, with inconsistent evidence across imaging phenotypes and limited investigation into gene–environment interactions. Method This cross-sectional study included 728 patients with chronic...

Feng Liu, Yulan Gou · 0 citations

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