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Author

Fengqin Zhu

3 papers indexed here

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Open access Sep 2026

EPS deficiency aggravates intestinal mucosal inflammation and dysbiosis through disrupting macrophage polarization balance in ulcerative colitis

Background Ulcerative colitis (UC) is a chronic, immune-mediated inflammatory bowel disorder, and macrophages are essential for maintaining intestinal mucosal balance during UC. Long intergenic non-coding RNA–erythroid prosurvival (lincRNA-EPS) is a novel lincRNA identified as a key inflammatory regulator. Nonetheless,...

Feng-Qin Zhu, Gui-Yuan Jin, Li-Hao Shi et al. · 0 citations
Open access Sep 2026

KARAP Deficiency Alleviates Intestinal Mucosal Barrier Dysfunction by Regulating Mitochondrial Homeostasis in Macrophages

Killer cell activating receptor-associated protein (KARAP) has been implicated in the progression of various inflammatory and immune-mediated diseases, including ulcerative colitis (UC). Although macrophages play a pivotal role in UC pathogenesis, how KARAP regulates macrophage immune responses remains poorly und...

Gui-Yuan Jin, Yong-Hong Yang, Feng-Qin Zhu et al. · 0 citations
Review Aug 2026

Novel Clinical Intervention Pathway Based on the Pathogenesis Mechanism of Enterotoxigenic Bacteroides fragilis.

This review systematically expounds on a variety of promising targeted therapeutic strategies against ETBF, clarifies their potential clinical application value and latest research progress, and provides a comprehensive theoretical framework for the clinical diagnosis, treatment and prognostic management of ETBF-associ...

Chun-Yu Wang, Li-Hao Shi, Gui-Yuan Jin et al. · 0 citations

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