Regioselective Insertion of Diazo Compounds Into 3‐Hydroxyisoindolinones for the Synthesis of Isoquinolones
Both 3‐hydroxyisoindolinones and isoquinolones are structural motifs found in many natural alkaloids, and their derivatives exhibit a wide range of therapeutic applications. Herein, we report the direct conversion of 3‐hydroxyisoindolinones into isoquinolones via a diazo ester insertion reaction. This transformation in...