Feng-Yen Lin

Deficiency of protein kinase Cδ reprograms macrophage immunometabolism to suppress pyroptosis and stabilize atherosclerotic plaques.

While atherosclerotic plaque vulnerability drives acute coronary syndrome, the regulatory mechanisms underlying plaque stability remain unclear. Protein kinase Cδ (PKCδ) has been implicated in atherosclerosis progression, but its specific role in plaque vulnerability and the underlying mechanisms require clarification....