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Feng-Ying Dong

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Open access Aug 2026

Inhibition of Xanthine Oxidase by Dietary Flavonoids: SWISS-MODEL-Based Docking, In Vitro Analysis, In Vivo Structure-Activity Investigations and Gut Microbiota-Based Systematic Toxicological Evaluation

Hyperuricemia (HUA), a prevalent metabolic disorder, needs new xanthine oxidase (XOD) inhibitor studies to reduce severe side effects. In this study, the inhibitory activities of 20 dietary flavonoids against XOD were determined in vitro, and a structure-activity relationship (SAR) model was subsequently developed....

Pingping Guo, Xing-Xing Liu, Feng-Ying Dong et al. · 0 citations

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