Open access
Sep 2026
Enhancing METTL3-mediated m6A modification of Fzd3 mRNA exhibits neuroprotection in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive loss of motor neurons (MNs). N 6 -methyladenosine (m 6 A) is the most abundant mRNA modification, yet its role in ALS MNs degeneration remains poorly understood. In this study we observed a significant...
Jinmeng Liu, Qiu Yan, Ying-Jun Guan et al.
· Cell Death & Disease · 0 citations