Fernando Calamante

Sleep spindles are linked to white matter connectivity differentially in older adults with and without cognitive impairment

Overall, white matter connectivity of the anterior thalamic radiation and superior longitudinal fasciculus was not robustly associated with sleep spindle density or slow oscillatory power in this at-risk cohort, but superior longitudinal fasciculus II connectivity may differentially relate to spindle amplitude in mild cognitive impairment, potentially reflecting altered thalamocortical network engagement in early neurodegeneration.