OBJECTIVE
The authors sought to identify plasma glial fibrillary acidic protein (GFAP) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) cutoffs corresponding to a range of high positive predictive values (PPVs) for detecting intracranial pathology on CT and detecting pathology on MRI (when CT is negative) in patients who...
Shawn R. Eagle, John K. Yue, A. Puccio et al.· Journal of Neurosurgery· 1 citation
OBJECTIVE
Emerging traumatic brain injury (TBI) guidelines increasingly recognize the role of blood-based biomarkers in improving diagnostic and triage accuracy, yet their integration into pediatric care remains limited and underexplored. This study examined the performance of a blood-based biomarker panel in predictin...
Andrew Reisner, A. Alawieh, J. Lepard et al.· Journal of Neurosurgery: Ped...· 0 citations
Inflammation following traumatic brain injury (TBI) may contribute to long-term morbidity. We aimed to characterize plasma interleukin-6 (IL6) trajectory after TBI and assess associations with imaging, biomarkers, and outcomes. Secondary analysis of three prospective multicenter observational cohorts: BIO-AX-TBI (Unite...
Leo Layzell, E. Kodosaki, Xiaoying Sun et al.· Neurotrauma Reports· 0 citations
Background and Purpose The timing of diagnosis is a critical factor that significantly impacts medical treatment and patient outcomes in individuals with intracerebral hemorrhage (ICH). The study primarily aimed to evaluate the diagnostic potential of four brain-specific biomarkers, glial fibrillary acidic protein (GFA...
Seza Apiliogullari, E. Elbayoumi, Nina S. Collier et al.· Biomarker Insights· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
