Author

Flavia Medeiros Savi

2 papers indexed here

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Open access Oct 2026

Repair of Full Thickness Articular Cartilage Using a 3D-Printed Acellular Polymer Implant in a Caprine Model: A Pilot Study

Objective Evaluate a 3D-printed acellular polymer scaffold combined with microfracture for repairing critical-sized cartilage defects in a goat model. Methods Six goats received bilateral 10 mm femoral condyle defects. In a paired design, one knee received microfracture plus a scaffold (95% or 45% infill); the contrala...

Flavia Medeiros Savi, Nathan J. Castro, B. Holmes et al. · Cartilage · 0 citations

Review Open access Aug 2026

Rethinking osteocyte models in vitro: the need for mineralised extracellular matrix and network architecture

Osteocytes inhabit one of the most extreme cellular microenvironments in the human body: a hydrated, hierarchically structured mineralised extracellular matrix where lacunar confinement, canalicular connectivity, fluid transport and mechanics are inseparable from cell function. In vitro osteocyte models have rapidly ad...

M. Morenc, Flavia Medeiros Savi, A. Tits et al. · Frontiers in Bioengineering... · 0 citations