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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Francesca Telese

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Open access Aug 2026

Trex-QTL: A mixture-model for identification of genetic effects with global effects on molecular phenotypes

While thousands of cis expression quantitative trait loci (cis-eQTLs) have been reliably identified, detecting trans-eQTL effects has proven to be challenging due to insufficient statistical power, lack of comparable tissues and cohorts, and low reproducibility across studies. Here, we present Trex-QTL, a novel trans-e...

Cynthia Wu, Andrey V. Bzikadze, Tian-Yao Xu et al. · 0 citations
Open access Aug 2026

Reelin coordinates neuronal positioning and Müller glia scaffold maturation during retinal development

Reelin is a secreted extracellular matrix protein that regulates neuronal migration and layer formation in the developing brain, yet its role in retinal development remains incompletely defined. Here, we investigated Reelin function in retinal lamination using wild-type and Reeler (Reln−/−) mice, combining stage-resolv...

Priya Purohit, Simran Purohit, Yinuo Meng et al. · 0 citations

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