Author

Francesco Calzaferri

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Review Open access Jul 2026

Targeting DNA Methylation: New Paradigms and the Advent of Gene-Selective Tools.

The mechanisms and roles of DNA methylation in epigenetic regulation are examined, the current landscape of DNA methylation modulators are evaluated, from traditional DNMT inhibitors to cutting-edge CRISPR-dCas9 fusion systems and protein-protein interaction disruptors, and their clinical relevance are evaluated.

Julie Gilbert, Francesco Calzaferri · Chemical Research in Toxicol... · 0 citations