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Francine Grodstein

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Open access Oct 2026

Brain DNA methylation, APOE genotype and Alzheimer's disease neuropathology in a large postmortem cohort.

DNA methylation (DNAm) plays a critical role in Alzheimer's disease (AD). Previous epigenome-wide association studies using 450K arrays captured limited CpG coverage and often focused on a single neuropathological measure. Here we profiled DNAm in 1,250 postmortem prefrontal cortex samples from the Rush Alzheimer's Dis...

G. Miao, Cheng Gao, Lei Yu et al. · 0 citations
Open access Aug 2026

Single‐Cell Analyses Reveal Dysregulation of Ribosomal Protein Genes During Hematopoietic Stem and Progenitor Cell Aging

This study identifies molecular signatures of systemic aging rooted in bone marrow HSPCs and suggests that dysregulated ribosomal protein gene expression is an under‐appreciated hallmark of hematopoietic stem cell aging.

Roger Atanga, Saurav Mallik, Soumita Seth et al. · 0 citations

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