Open access
Aug 2026
PqqU (PA2289) is the primary PQQ transporter in Pseudomonas aeruginosa and links carbon metabolism to iron homeostasis.
Pseudomonas aeruginosa relies on the redox cofactor pyrroloquinoline quinone (PQQ) for efficient glucose and ethanol metabolism via periplasmic dehydrogenases (Gcd and ExaA). While PQQ biosynthesis is well-characterized, its uptake mechanisms remain unclear. Here, we identify PA2289 (PqqU), a TonB-dependent transporter...
C. Paschalidis, Manon Ferry, Anne-Eloïse Revillot-Schmidt et al.
· FEMS Microbiology Letters · 0 citations