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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Françoise Ochsenbein

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Open access Nov 2026

A structural model for the autoinhibition of the γ-TuRC-activating CM1 domain.

Microtubule nucleation by γ-tubulin ring complexes (γ-TuRCs) must be spatiotemporally controlled to avoid major cell division errors. γ-TuRCs are activated by the centrosome-specific binding of a highly conserved centrosomin motif 1 (CM1) domain, but how binding is prevented in the cytosol remains unclear. We provide t...

Abir Elfarkouchi, A. Vitard, Léa Mammri et al. · 0 citations

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