Fransiska Ambarukmi Pontjosudargo

Emerging opportunities in network pharmacology mechanisms of Saussurea costus in regulating inflammation and intestinal barrier dysfunction in non-alcoholic fatty liver disease

Background: Non-alcoholic fatty liver disease (NAFLD) is a heterogeneous metabolic liver disorder involving excessive lipid deposition, redox imbalance, inflammatory activation, and disruption of gut-liver axis homeostasis. Loss of epithelial junction integrity and increased intestinal permeability are increasingly con...