Author

Frederick K. Korley

3 papers indexed here

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Oct 2026

Clinical cutoffs for plasma biomarkers to identify intracranial pathology in traumatic brain injury patients with Glasgow Coma Scale scores 13 to 15: a TRACK-TBI study.

OBJECTIVE The authors sought to identify plasma glial fibrillary acidic protein (GFAP) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) cutoffs corresponding to a range of high positive predictive values (PPVs) for detecting intracranial pathology on CT and detecting pathology on MRI (when CT is negative) in patients who...

Shawn R. Eagle, John K. Yue, A. Puccio et al. · Journal of Neurosurgery · 1 citation

Open access Sep 2026

Comparability of GFAP and UCH-L1 Measurements Using Handheld and Core Laboratory TBI Plasma Tests and Their Diagnostic Performance for Traumatic Intracranial Lesions.

BACKGROUND Glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) are cleared by the U.S. Food and Drug Administration (FDA) to aid computed tomography (CT) decision-making in patients with traumatic brain injury (TBI). Two commercial assays, i-STAT TBI Plasma test and Alinity i TBI...

Nathan B. Roberts, C. Gherasim, Ke-Xin Li et al. · The Journal of Applied Labor... · 0 citations

Oct 2026

A-359 Comparison of Whole Blood and Plasma GFAP and UCH-L1 Blood-Based Biomarkers for Screening Patients with Mild Traumatic Brain Injury

The diagnosis of traumatic brain injury (TBI) in the emergency department can be challenging and typically relies on brain CT scans, which carry associated costs and risks from ionizing radiation. Blood-based biomarkers, such as glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (U...

Melissa Boyd, Corrine Potocki, Frederick K. Korley et al. · Clinical Chemistry · 0 citations