Fritjof Havemeister

Aggregation, Propagation and Pathological Implications of α-synuclein Amyloid Fibrils in Parkinson’s Disease

Parkinson’s disease (PD) is a severe, progressive neurodegenerative disorder characterized by aggregation of the protein α-synuclein into amyloid fibrils, leading to the formation of Lewy bodies and Lewy neurites and degeneration of dopaminergic neurons in the substantia nigra. Although α-synuclein aggregation is a def...