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Author

Fu-Jian Ji

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Open access Sep 2026

Zearalenone exposure is associated with increased tumor burden and coordinated host-microbiota-metabolic alterations in colitis-associated colorectal cancer.

Zearalenone (ZEN) is a common foodborne mycotoxin with intestinal toxicity, but its role in colitis-associated colorectal cancer (CAC) remains unclear. This study evaluated the association between ZEN exposure and CAC progression and explored the related molecular, microbial, and metabolic alterations. Network toxicolo...

Kun Wu, Jia-Qi Wang, Xin-Yi Gao et al. · 0 citations
Review Open access Sep 2026

The plasticity and metabolic reprogramming of macrophage in ulcerative colitis

Macrophages exhibit phenotypic plasticity, which plays a role in driving tissue injury and promoting mucosal repair in ulcerative colitis (UC). Intestinal macrophages originate from both embryo-derived resident cells and circulating monocytes. Macrophage polarization influences inflammatory responses and is regulated b...

Yi Zhang, Ding-Quan Yang, Jun-Nan Jiang et al. · 0 citations

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