Neutrophil-Membrane Camouflaged Nanoparticles for Dual Suppression of Pro-Inflammatory Macrophages and Oxidative Stress in Septic Acute Lung Injury.
Management of sepsis-associated acute lung injury (S-ALI) remains challenging due to complex inflammatory cascades, oxidative stress amplification, and limited therapeutic delivery to injured pulmonary tissues. Here, we developed a biomimetic "dual-lock-inspired" nanoplatform (M@ORNP) that integrates a neutrophil-mimet...