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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Fu-Ren Zhang

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Open access Sep 2026

Efficacy and Safety of Recibokibart, an Interleukin-36 Receptor Antibody, in Generalized Pustular Psoriasis: A Phase 2 Randomized Trial.

BACKGROUND Generalized pustular psoriasis (GPP) is a rare, severe inflammatory skin disease characterized by acute flares. Recibokibart is a humanized IgG1 monoclonal antibody targeting the interleukin-36 (IL-36) receptor. In a phase 1b open-label study, a single intravenous dose of recibokibart was associated with an...

Bao-Qi Yang, Yu-Zhen Li, Yu Wang et al. · 0 citations
Open access Aug 2026

Shared and Distinct T‑Cell Receptor Characteristics of CD4+ and CD8+ Drug-Specific T‑Cells In Vitro Generated from Healthy Donors and Hypersensitive Patients

The initiation of T-cell-mediated drug hypersensitivity reaction requires the formation of a human leukocyte antigen (HLA)-peptide-drug-T-cell receptor (TCR) complex. While specific interactions between HLA molecules and drug antigens are well-defined, the characteristics of drug binding to the TCR are unclear. Herein,...

Kanoot Jaruthamsophon, Paul J. Thomson, J. Pratoomwun et al. · 0 citations

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